Carboxymethyl chitosan reduces inflammation and promotes osteogenesis in a rabbit knee replacement model
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چکیده
منابع مشابه
Carboxymethyl-chitosan protects rabbit chondrocytes from interleukin-1beta-induced apoptosis.
Chondrocyte apoptosis is important in pathogenesis of osteoarthritis. Chitosan is a non-toxic, biodegradable and biocompatible glycosaminoglycan. In this study, the effects of carboxymethyl-chitosan (CM-chitosan), a soluble derivative of chitosan, on chondrocyte apoptosis were investigated. Primary rabbit chondrocytes were cultured and induced to apoptosis by 10 ng/ml interleukin-1beta (IL-1bet...
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ژورنال
عنوان ژورنال: BMC Musculoskeletal Disorders
سال: 2020
ISSN: 1471-2474
DOI: 10.1186/s12891-020-03803-3